Grape Seed Extract Hair Loss Study – Does it Work?

grapeseed extract hairloss study

Grapes have been consumed by humans for thousands of years in addition to being used for medicinal purposes. Egyptians ate grapes more than 6000 years ago and Greek philosophers talked of grape wine having healing powers.  These sweet, round berry fruits, according to research, are endowed with numerous vitamins, nutrients, and complexes that give them their curative powers.  Traditional European healers used grapevine extract to treat eye and skin diseases.

Grape seed extract is the product of crushed seeds of wine grapes and has been an important component in the diet and medicinal shelves of many cultures worldwide. Grape seed extract contains Procyanidin oligomers, Vitamin E, flavonoids and linoleic acid which are a natural constituent of grape seeds. While there is a very small possibility of grape seed alone triggering the growth of receding hair, its beneficial constituents can impact a number of mechanisms that affect hair loss. Grape seed extract is therefore viable for use as a hair loss treatment according to findings of a recent Japanese hair loss study.

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Research on Grape Seed Extract and Hair Loss

Although there is no research that has been done to prove the effect of grape seed extract on receding hair in humans, several studies performed on animals have proved that the constituents of grape seed extract can minimize hair loss and consequently promote the growth of hair.

In 1998, Japanese researchers studied the effect of grape seed extract on the loss of hair and found out that it was capable of promoting the conversions of the hair cycle. In this study performed at the Tsukuba Research Laboratories, 8 weeks old mice were placed in three groups. In the first group nothing was applied to the hair, in the second there was topical application of Minoxidil and in the third, a 3% proanthocyanidins that were extracted from grape seeds that were applied.

The age of the mice was purposely chosen because from 4 to 14 weeks C3H mice have been found to experience hair loss (telogen/resting phase). The study lasted for 19 days after which the findings were recorded. Group A showed the highest amount of hair loss (60-70%), group B that was treated with Minoxidil showed 80-90 percent of hair growth while group C that received topical application of proanthocyanidins showed about 90-100 hair coverage. The findings of the study were published in November 1998 issue of the Acta Derm Venereol, a Swedish journal.
This study proved that indeed the Minoxidil and proanthocyanidins promoted a fast hair growth by taking follicles from the resting (telogen phase) to the active (anagen) phase.

Can Grape seed be used in treating Androgenetic Alopecia (male-pattern baldness)?

Androgenetic Alopecia, also called male-pattern baldness, is a condition where the hair cycle becomes short as a result of miniaturization of follicles caused by the presence of DHT. The hair loss study undertaken by the Japanese has proven that grape seed extract can indeed jumpstart the hair cycle and activate follicles in the telogen phase where associated with the most hair loss.

Grape seed extract also has medicinal qualities which can prevent the hair follicles of a person suffering from hair loss from suffering irreparable damage. Promote the healing process; a person with Androgenetic Alopecia should keep their hair clean at all times.

There are several reasons that make it possible for the grape seed to be used as a treatment for hair loss. To begin with, it contains oligomeric proanthocyanidins which are found in grape seeds have been found to inhibit the production of DTH which is a major contributing factor to hair loss. At the same time, OPC’s stimulate the production of hair follicles and lowers the DHT amounts in the follicles. Healthy follicles promote the growth of new, healthy and fast-growing hair.

The essential fatty acids and high vitamin E levels contained in grape seeds are also vital for healthy hair. These nutrients have anti-inflammatory properties and are also rich in anti-oxidants which not only promote the growth of hair but are also beneficial to the overall health.

Grape seed extract further contributes to the growth of hair by promoting a healthy skin. Improved microcirculation in the capillaries near the skin accelerates the nourishment of hair follicles and the rate of their oxygen acquisition. Nitric oxide is also produced at these sites. Nitric oxide is a vaso-relaxant since it can dilate blood vessels. The combined effect of the nitric oxide produced and the microcirculation in the capillaries promote the growth of hair even further.

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How to Add Grape Seed Extract For Hair Growth to Your Daily Hair Care Routine

If you find the research done on grape seed extract and hair beneficial to your particular case you can try out the treatment and see if it will work for your particular case. There are several ways you can add grape seed extract to your daily hair care routine.

Grape seed oil can today be found in many forms. It is easy to use and can either be used in a topical application or be taken orally. There is also a wide variety of shampoos, lotions, and creams containing grape seed extract.
If you choose to use the liquid form of grape seed extract you can apply it directly to your scalp and hair. This is the easiest way of integrating grape seed oils which you can either purchase from the stores or make by yourself through a cold press procedure.

Apply the grapeseed oil directly on your scalp after a shower and massage in a circular motion. Allow it to stay overnight or rinse it off after about 20 minutes.


While it is possible to use grape seed extracts and oils to reduce hair loss, there is no conclusive evidence that it will give 100% success result when used on baldness. You can get hope from the tests performed on the lab mice and try out the grape seed extract, either homemade or purchased and find out if it will work for you.

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